What lineage do mast cells come from?

What lineage do mast cells come from? Mast cells are originated from pluripotent progenitor cells of the bone marrow, and mature under the influence of the c-kit ligand and stem cell factor in the presence of other distinct growth factors provided by the microenvironment of the tissue where they are […]

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What is Tubulointerstitial nephropathy?

What is Tubulointerstitial nephropathy? Tubulointerstitial nephritis (TIN) is a frequent cause of acute kidney injury (AKI) that can lead to chronic kidney disease (CKD). TIN is associated with an immune-mediated infiltration of the kidney interstitium by inflammatory cells, which may progress to fibrosis. What does Tubulointerstitial mean? The term tubulointerstitial […]

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