What is the chemical formula for aspirin?
Chemical formula = C9H8O4 or CH3COOC6H4COOH or HC9H7O4 Aspirin is prepared by chemical synthesis from salicylic acid, through acetylation with acetic anhydride. The molecular weight of aspirin is 180.16g/mol. It is odourless, colourless to white crystals or crystalline powder.
What is the decomposition of aspirin?
Aspirin decomposes rapidly in solutions of ammonium acetate or the acetates, carbonates, citrates, or hydroxides of the alkali metals. It is stable in dry air, but gradually hydrolyses in contact with moisture to acetic and salicylic acids.
What type of reaction is aspirin synthesis?
The synthesis of aspirin is classified as an esterification reaction. Salicylic acid is treated with acetic anhydride, an acid derivative, causing a chemical reaction that turns salicylic acid’s hydroxyl group into an ester group (R-OH → R-OCOCH 3).
How does aspirin affect COX1 and COX2?
COX-1 and COX-2 inhibition At least two different types of cyclooxygenases, COX-1 and COX-2, are acted on by aspirin. Aspirin irreversibly inhibits COX-1 and modifies the enzymatic activity of COX-2. COX-2 normally produces prostanoids, most of which are proinflammatory.
Is aspirin a cyclooxygenase inhibitor?
Aspirin is classified as a non-selective cyclooxygenase (COX) inhibitor and is available in many doses and forms, including chewable tablets, suppositories, extended release formulations, and others. Acetylsalicylic acid is a very common cause of accidental poisoning in young children.
Does aspirin acetylate p21Cip1?
“Aspirin inhibits camptothecin-induced p21CIP1 levels and potentiates apoptosis in human breast cancer cells”. International Journal of Oncology. 34 (3): 597–608. doi: 10.3892/ijo_00000185. PMID 19212664. ^ Alfonso LF, Srivenugopal KS, Bhat GJ (2009). “Does aspirin acetylate multiple cellular proteins? (Review)”.
What does ag2s2o3 stand for?
Ag2S2O3 silver nitrate sodium thiosulfate sodium nitrate 2 1 2 1 Hệ số Nguyên – Phân tử khối (g/mol) Số mol Khối lượng (g)
How is aspirin identified in the US Pharmacopeia?
The United States Pharmacopeia, USP 30/The National Formulary, NF 25; Rockville, MD: U.S. Pharmacopeial Convention, Inc., p.1443 (2007) Analyte: aspirin; matrix: chemical identification; procedure: dissolution in water; reaction with ferric chloride to produce a violet-red color U.S. Pharmacopeia.