Can Microsporum canis be treated?
Treatment. Microsporum canis infections can be easily managed by topical antifungal agents; however severe cases may necessitate systemic therapy with griseofulvin, itraconazole or terbinafine.
What is the treatment for Microsporum?
A variety of oral and topical antifungal agents is available and drugs such as griseofulvin (Gri), terbinafine (TER), itraconazole (IT), and fluconazole (FLZ) are used to cure severe infections in humans and animals [2,13,14].
Does Microsporum canis affect humans?
Microsporum canis is a dermatophyte fungus of which cats and dogs are recognized as the natural hosts. M. canis is also easily transmitted to humans, causing lesions to the glabrous skin (tinea corporis) and to the head (tinea capitis).
How do you treat microsporum Gypseum?
Oral ketoconazole with topical enilconazole has been found to help treat skin lesions. Animal treatment is usually done with itraconazole or ketoconazole; most European countries use off label terbinafine in cats and dogs.
What kills Microsporum canis?
There are very few agents that effectively kill Microsporum canis in the environment. Research by Moriello et al, identified only 3 highly effective ingredients (bleach, 1% formalin, and enilconazole).
What is the incubation period for Microsporum gypseum?
Infection occurs by contact with viable spores from infected hair on infected animals or people, on contaminated fomites (especially tack and grooming equipment), and in contaminated soil. The incubation period is 1–4 wk.
How does Microsporum canis growth?
Spores are very resistant, attach to the skin and germinate producing hyphae, which will then grow in the dead, superficial layers of the skin, hair or nails. Similar to other fungal dermatophytes, M. canis also secretes keratinolytic protease and gains energy from keratin in nails, hair, and skin.
What does microsporum Gypseum cause?
Dermatophytosis caused by M. gypseum usually manifests as an inflammatory mycosis that typically affects the glabrous skin and scalp, especially in children. Rarely, it can present as onychomycosis.