What causes high DHEA in children?
An excess of DHEA-S may be caused by congenital adrenal hyperplasia (a condition present from birth in which the adrenal glands make too much androgen and not enough of other steroid hormones) or some other adrenal problems. Low levels of DHEA-S may be present if the adrenal glands are damaged or diseased.
What is the normal range of DHEAS?
Normal Results Ages 20 to 29: 65 to 380 µg/dL or 1.75 to 10.26 µmol/L. Ages 30 to 39: 45 to 270 µg/dL or 1.22 to 7.29 µmol/L. Ages 40 to 49: 32 to 240 µg/dL or 0.86 to 6.48 µmol/L. Ages 50 to 59: 26 to 200 µg/dL or 0.70 to 5.40 µmol/L.
What is a high level of DHEAS?
If your results show high levels of DHEA sulfate (DHEAS), it may mean you have one of the following conditions: Congenital adrenal hyperplasia, an inherited disorder of the adrenal glands. A tumor of the adrenal gland. It may be benign (noncancerous) or cancerous.
What do DHEA levels tell you?
DHEAS Test (DHEA Sulfate Test) Healthcare providers use DHEAS tests to measure levels of a steroid hormone that your body converts into estrogen and androgens (testosterone). A high test result may indicate an adrenal tumor or polycystic ovary syndrome (PCOS), while a low test result may indicate Addison’s disease.
Is DHEA and DHEAS the same?
What Is the Difference Between DHEA and DHEA,s? The main differentiator between DHEA and DHEA sulfate is that DHEA has an extra sulfate molecule attached to it. DHEA,s is a steroid androgen that is found in both women and men. DHEA is made in the ovaries, testes and the adrenal glands.
How do I lower DHEA-S?
Drugs that can decrease or lower the levels of DHEA in the body include:
- Antipsychotic medications, including chlorpromazine (Thorazine) and quetiapine (Seroquel)
- Budesonide (Pulmicort)
- Estrogens.
- Oral contraceptives (birth control pills)
- Dexamethasone (Decadron)
- Metformin (Glucophage)
How do I lower DHEAS?
Can high DHEA levels cause anxiety?
May cause agitation, delusions, nervousness, irritability, or psychosis and may induce hypomanic, aggressive, psychotic, or disinhibited behavior. In people with bipolar disorder, DHEA should be used with caution and only in low doses because it can exacerbate mania, irritability, and aggression.
What does a low DHEAS Mean?
A low level of DHEA-S might mean: A damaged adrenal gland. Addison’s disease, a rare condition that causes weak muscles, lack of energy, weight loss, and low blood pressure. Hypopituitarism, a rare hormonal disease that can lead to tiredness, low sex drive, infertility, weight loss, and short height in children.
Why is DHEAS high in PCOS?
Although ovaries are the main source of increased androgens in the syndrome, between 20 and 30% of patients with PCOS can have excess androgens from an adrenal source, manifested as elevated dehydroepiandrosterone sulfate (DHEAS) levels.
Does PCOS cause high DHEA levels?
High DHEAS levels are found in 22–25% of patients with PCOS (10). However, some studies have reported frequencies of DHEAS levels as high as 48–52% in PCOS (11). Another finding is that patients with high DHEAS levels are younger, thinner, and more hirsute than PCOS patients with normal DHEAS levels (10).
What are the side effects of low DHEA?
Because levels of DHEA decline with age, researchers have wondered if DHEA could work as an anti-aging treatment. In older people, lower than normal levels of DHEA have been associated with osteoporosis, heart disease, memory loss, and breast cancer.
Why DHEA is so important?
Why do people take DHEA? A number of studies have found that DHEA supplements may help people with depression, obesity, lupus, and adrenal insufficiency. DHEA may also improve skin in older people and help treat osteoporosis, vaginal atrophy, erectile dysfunction, and some psychological conditions.
How do you treat high DHEAS?
How do I lower DHEAs?